Urticaria pigmentosa
Is e Urticaria pigmentosa an seòrsa mastocytosis cutaneous as cumanta. Is e galar tearc a th’ ann air adhbhrachadh le cus àireamh de chrann-cheallan sa chraiceann a bheir gu buil dubhan no lotan air a’ chraiceann nuair a tha iad iriosal. Gu tric chithear spotan dearg no donn air a’ chraiceann, mar as trice timcheall air a’ bhroilleach, a’ mhaoil, agus air ais. Bidh na crann-ceallan sin, nuair a tha iad iriosal (me le bhith a’ suathadh a’ chraicinn, foillseachadh teas), a’ toirt a-mach cus histamine, a’ toirt air adhart ath-bhualadh mothachaidh a dh’ adhbhraicheas dubhan a tha ionadail don raon irioslachaidh, ris an canar uaireannan “soidhne Darier”.
☆ Ann an toraidhean 2022 Stiftung Warentest às a’ Ghearmailt, cha robh sàsachd luchd-cleachdaidh le ModelDerm ach beagan nas ìsle na le co-chomhairlean telemedicine pàighte.
Tha e buailteach tachairt air torso clann òga.
References
Tha Mastocytosis na chumha far a bheil cus cheallan crann ann, a lorgar gu tric ann an grunn phàirtean den bhodhaig mar an craiceann, smior cnàimh, agus an siostam cnàmhaidh. A rèir Buidheann Slàinte na Cruinne (WHO) , faodar cutaneous mastocytosis a roinn ann an trì prìomh sheòrsan. Tha a’ chiad sheòrsa (mastocytomas) air a dhèanamh suas de leòintean aonaranach no beagan (≤3) . Tha an dàrna seòrsa (urticaria pigmentosa) a' gabhail a-steach iomadach leòintean, mar as trice a' dol bho barrachd air 10 gu nas lugha na 100. Tha an seòrsa mu dheireadh a' sealltainn com-pàirt farsaing air feadh a' chraicinn. Is e Urticaria pigmentosa an seòrsa mastocytosis cutaneous as cumanta ann an clann, ach faodaidh e tachairt ann an inbhich cuideachd. Mar as trice is e suidheachadh gun chron a th’ ann a bhios gu tric a’ fàs nas fheàrr aig àm òigeachd. Eu-coltach ri mastocytosis inbheach, is ann ainneamh a bhios urticaria pigmentosa a’ toirt buaidh air buill-bodhaig a-staigh. Is e aon fheart sònraichte de urticaria pigmentosa gu bheil e buailteach a bhith ag adhbhrachadh spotan beaga, tachaiseach, ruadh-dhonn, neo buidhe-dhonn no lotan air a’ chraiceann, ris an canar gu tric dubhagan. Mar as trice bidh na spotan sin a’ nochdadh ann an leanabachd agus mairidh iad fad beatha.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Thàinig nighean 6-bliadhna a-steach le grunn spotan dorcha a nochd an toiseach air a sgalp agus an uairsin a sgaoil gu a h-aodann agus a corp thairis air na sia mìosan a dh’ fhalbh. Thug i iomradh air a bhith gam faireachdainn ag èirigh, a’ tionndadh dearg, agus tachas nuair a chaidh cuideam a chuir an sàs. Cha d’ fhuair i eòlas air sruthadh, cuir a-mach, a’ bhuineach no wheezing, agus cha tug na h-eachdraidh mheidigeach pearsanta is teaghlaich aice sanasan iomchaidh seachad. Às deidh dhuinn sgrùdadh a dhèanamh, lorg sinn grunn spotan dorcha air a craiceann, a maoil, a h-aodann, agus amhach, còmhla ri badan dorcha beagan àrdaichte air a broilleach agus air ais. Le bhith a’ suathadh gu h-aotrom air na spotan dh’ adhbhraich iad sèid agus tachas fhèin taobh a-staigh 2 mhionaid, ach chaidh na comharraidhean sìos taobh a-staigh 15-20 mionaid (Darier's sign) .
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
